Viamet is a biopharmaceutical company focused on the discovery, development and commercialization of novel antifungal agents based on its proprietary metalloenzyme medicinal chemistry platform, the Metallophile Technology. Metalloenzymes are enzymes that contain a metal, such as iron, zinc or copper, which is linked to the enzyme's protein component. Drugs based upon this platform are expected to have greater selectivity, fewer side effects and improved potency compared to currently available antifungal agents. The company's lead product candidate, VT-1161, is an oral agent in Phase 2b development for the treatment of recurrent vulvovaginal candidiasis, or RVVC, a highly prevalent mucosal infection for which there are no approved therapies in the United States, and onychomycosis, a very common fungal infection of the nail for which current treatments are suboptimal with respect to safety, tolerability and efficacy. Additional product candidates in preclinical development include VT-1129, which is targeted for the treatment of cryptococcal meningitis, and VT-1598 and related analogues, which are targeted for the treatment of invasive fungal infections.

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