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VC-funded Company:

XTuit Pharmaceuticals
Lab Central, 700 Main Street
Cambridge, MA 02139
Phone: 781-290-0770

XTuit Pharmaceuticals, Inc. is a biopharmaceutical company developing novel microenvironment-activated therapeutics targeting key mechanisms resulting in hypoxia, decreased drug uptake, drug resistance, and decreased immune response. The Company's proprietary drug development pipeline and integrated, sophisticated clinical biomarker platform will be used for accelerated clinical development across selected cancers and fibrotic disorders. XTuit's compounds act through pleiotropic mechanisms to inhibit extracellular matrix synthesis and stabilization, and to silence activated stromal cells, including cancer-associated fibroblasts and stellate cells. As a result, XTuit compounds alleviate hypoxia and enable enhanced drug uptake through solid stress reduction. Moreover, the drugs have been shown to down-regulate stroma-induced tumor and inflammation signaling pathways to overcome treatment resistance.

Key Contact
Rakesh K. Jain, Ph.D.
Funding Events

06/11/15 $22,000,000 Series A Arcus Ventures
CTI Life Sciences
Omega Funds
Polaris Partners